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He began his career as a Research Associate at the Institute of Stable Isotopes in Tbilisi, Georgia, where he was working on the development of the novel techniques of separating carbon isotopes for medical and military applications.
He received additional training in the Institute of Physical Chemistry, Moscow, from to under the mentorship of Alexander Chaikin. Bekker presented the results of his research on the mechanism of hydrogen-fluorine chain reactions at several national conferences.
His research focused on developing advanced technologies for reducing emissions associated with carbon-based fuel. During his tenure at Allied, he advanced a new process of converting heavy hydrocarbons to fuels using supercritical fluids.
In , Bekker enrolled in the Master of Engineering Program at the New Jersey Institute of Technology, which he completed in and enrolled in the PhD program at the same institution.
The focus of Bekker's research at that time was changing from chemical to biomedical engineering. His doctoral thesis, "Transient Analysis of Macromolecular Blood-Tissue Exchange in Microvascular Bed," added in the understanding of transendothelial transport of monoclonal antibodies.
The results of this work were presented at various forums and published in several publications, including one in Circulation Research.
Mathematical modeling of biological systems sparked Bekker's interest in applying engineering principles to the analysis of the effects of drugs on mammalian circulation.
Practical applications of this approach required understanding of the pathophysiology of the diseases, so Bekker started his study of Medicine in and completed a four-year medical school program at the Rutgers New Jersey Medical School in , which was followed by a residency training in Anesthesiology at Columbia-Presbyterian Medical Center in New York.
Bekker's work in the area of computer simulation of physiological systems was recognized nationally. He was invited to speak at the meetings organized by the American Society of Anesthesiology , Society for Technology in Anesthesia, as well as at various regional conferences.
His clinical work was focused on providing perioperative care for neurosurgical patients. In , Bekker was appointed Chief of Neuroanesthesia Service.
He also directed Clinical Research in the Department. In , Bekker was promoted to the academic rank of Associate Professor of Anesthesiology with a joint appointment in the Department of Neurosurgery.
In addition to his clinical research, Bekker established Basic Research Lab.